longevity, telomeres 0
The title of Jean M. Hébert’s recently published book, Replacing Aging, fits the book nicely. Another title that would...
longevity 2
Peter Diamandis has pitched the new product of OneSkin Technologies, a company that claims to be able to reverse...
In my last post, I outlined David Sinclair’s anti-aging levels 1 and 2. Whereas levels 1 and 2 can,...
longevity, supplements 0
In my last post, I outlined David Sinclair's information theory of aging which claims to explain why we age....
David Sinclair is one of the most renowned scientists working on biological aging. He has published a new book...
longevity, telomeres 5
I think I bought this book the day it came out and read it immediately, putting aside another book,...
I just finished reading the The Telomere Effect by Nobel laureate Elizabeth Blackburn and Elissa Epel (2017). I was...
Elena Milova writes about a new survey asking people how long they'd like to live under different conditions. The...
In Cracking the Aging Code - The New Science of Growing Old-And What It Means for Staying Young, Josh...
Recently, I watched an interview where Ray Kurzweil talked with Aubrey de Grey. For me, the most interesting part...
Michael Pietroforte commented on Diamandis and OneSkin OS-01: Reverse the biological age of your skin by clearing senescent cells 2 weeks, 4 days ago
Gary, thanks! To make sure that it is not wishful thinking I recommend to make pictures (close-ups) once a week under the same light conditions. After a few months, you can show them to friends and ask them which skin looks younger.
Gary Bonkowski commented on Diamandis and OneSkin OS-01: Reverse the biological age of your skin by clearing senescent cells 2 weeks, 5 days ago
Michael, thanks for this review, I am a middle aged man with sun damage as a retired Army officer – lots of time in the desert… I started using OS-01 a couple of weeks ago and have used as directed, application twice daily; morning and night. I have seen some…
Eugene commented on David Sinclair’s level 3: Reversing aging with the Yamanaka factors 2 months, 4 weeks ago
Terrific article
Michael Pietroforte wrote a new post, Book review of Jean Hebert's "Replacing Aging," part 1: Why gerontology is not the solution 3 months, 2 weeks ago
The title of Jean M. Hébert’s recently published book, Replacing Aging, fits the book nicely. Another title that would fit even better (but wouldn’t sound so appealing) would be “Replacing Anti-aging Research.” In the first part, Professor Hébert of the Albert Einstein College of Medicine essentially dismantles all major approaches…
Michael Pietroforte wrote a new post, Diamandis and OneSkin OS-01: Reverse the biological age of your skin by clearing senescent cells 5 months, 1 week ago
Peter Diamandis has pitched the new product of OneSkin Technologies, a company that claims to be able to reverse the biological age of your skin by clearing senescent cells. In this post, I summarize the science behind this new approach to skin anti-aging.
Michael Pietroforte wrote a new post, David Sinclair’s level 3: Reversing aging with the Yamanaka factors 7 months, 2 weeks ago
In my last post, I outlined David Sinclair’s anti-aging levels 1 and 2. Whereas levels 1 and 2 can, at best, slow the aging process, level 3 has the potential to provide a real cure for aging. At level 3, at least in theory, we can completely reverse the age…
Nice! I know Aubrey but I have never read about his theory in detail, only very superficially. I agree that the Yamanaka factors seem to be the most promising ones. They are also the most exciting ones, the idea of reversing aging is just amazing! I’m not old, I’m 27,…
Michael Pietroforte commented on A summary of David Sinclair’s Information Theory of Aging 8 months ago
I think what he says about stress is consistent. Stress causes damage which causes aging. Moderate stress makes cells hunker down and focus on repairing damage. Thus, moderate stress slows aging, too much stress accelerates aging. Where I can’t follow is his claim that energy costs prevent cells from repairing…
Yeah, I’m reading the book and I didn’t understand his argument in the beginning. This is why I looked for an explanation and found your website. It seems a little contradictory indeed because it is not the damage itself that causes aging but the lack of sirtuins in the epigenome.…
